Immunogenicity of conjugate vaccines consisting of pneumococcal capsular polysaccharide types 6B, 14, 19F, and 23F and a meningococcal outer membrane protein complex.

In an effort to prepare pneumococcal (Pn) capsular polysaccharide (Ps) vaccines that would be immunogenic in infants, covalent conjugates were prepared for Pn types 6B, 14, 19F, and 23F. Each Ps type was covalently bound to an outer membrane protein complex from Neisseria meningitidis serogroup B an...

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Autori principali: Vella, P P, Marburg, S, Staub, J M, Kniskern, P J, Miller, W, Hagopian, A, Ip, C, Tolman, R L, Rusk, C M, Chupak, L S
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1992
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC258265/
https://ncbi.nlm.nih.gov/pubmed/1452327
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