Antigen-Specific T-Cell Responses in Humans after Intranasal Immunization with a Meningococcal Serogroup B Outer Membrane Vesicle Vaccine

We have studied the ability of the Norwegian group B meningococcal outer membrane vesicle (OMV) vaccine, when administered intranasally without adjuvant, to induce T-cell responses in humans. A group of 12 vaccinees was immunized with four doses of OMVs (250 μg of protein/dose) at weekly intervals,...

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Autors principals: Oftung, Fredrik, Næss, Lisbeth Meyer, Wetzler, Lee M., Korsvold, Gro Ellen, Aase, Audun, Høiby, E. Arne, Dalseg, Rolf, Holst, Johan, Michaelsen, Terje E., Haneberg, Bjørn
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
Matèries:
Microbial Immunity and Vaccines
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC96405/
https://ncbi.nlm.nih.gov/pubmed/9916109
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