KIS protects against adverse vascular remodeling by opposing stathmin-mediated VSMC migration in mice

Vascular proliferative diseases are characterized by VSMC proliferation and migration. Kinase interacting with stathmin (KIS) targets 2 key regulators of cell proliferation and migration, the cyclin-dependent kinase inhibitor p27(Kip1) and the microtubule-destabilizing protein stathmin. Phosphorylat...

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Bibliographic Details
Main Authors: Langenickel, Thomas H., Olive, Michelle, Boehm, Manfred, San, Hong, Crook, Martin F., Nabel, Elizabeth G.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2008
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582439/
https://ncbi.nlm.nih.gov/pubmed/19033656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33206
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