MTHFR 677C → T genotype disrupts prefrontal function in schizophrenia through an interaction with COMT 158Val → Met

Understanding how risk genes cumulatively impair brain function in schizophrenia could provide critical insights into its pathophysiology. Working memory impairment in schizophrenia has been associated with abnormal dopamine signaling in the prefrontal cortex, which is likely under complex genetic c...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Roffman, Joshua L., Gollub, Randy L., Calhoun, Vince D., Wassink, Thomas H., Weiss, Anthony P., Ho, Beng C., White, Tonya, Clark, Vincent P., Fries, Jill, Andreasen, Nancy C., Goff, Donald C., Manoach, Dara S.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2008
विषय:
Biological Sciences
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582272/
https://ncbi.nlm.nih.gov/pubmed/18988738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803727105
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