Enhanced A(3 )adenosine receptor selectivity of multivalent nucleoside-dendrimer conjugates

BACKGROUND: An approach to use multivalent dendrimer carriers for delivery of nucleoside signaling molecules to their cell surface G protein-coupled receptors (GPCRs) was recently introduced. RESULTS: A known adenosine receptor (AR) agonist was conjugated to polyamidoamine (PAMAM) dendrimer carriers...

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Bibliographic Details
Main Authors: Klutz, Athena M, Gao, Zhan-Guo, Lloyd, John, Shainberg, Asher, Jacobson, Kenneth A
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582240/
https://ncbi.nlm.nih.gov/pubmed/18947419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-3155-6-12
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