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A molecular signaling model of platelet phosphoinositide and calcium regulation during homeostasis and P2Y(1) activation
To quantify how various molecular mechanisms are integrated to maintain platelet homeostasis and allow responsiveness to adenosine diphosphate (ADP), we developed a computational model of the human platelet. Existing kinetic information for 77 reactions, 132 fixed kinetic rate constants, and 70 spec...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2581995/ https://ncbi.nlm.nih.gov/pubmed/18596227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-157883 |
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