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Effect of Ames dwarfism and caloric restriction on spontaneous mutation frequency in different mouse tissues
Genetic instability has been implicated as a causal factor in cancer and aging. Caloric restriction (CR) and suppression of the somatotroph axis significantly increase life span in the mouse and reduces multiple symptoms of aging, including cancer. To test if in vivo spontaneous mutation frequency i...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2581895/ https://ncbi.nlm.nih.gov/pubmed/18565572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2008.04.013 |
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