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Prevention of Neuromusculoskeletal Frailty in Slow-Aging Ames Dwarf Mice: Longitudinal Investigation of Interaction of Longevity Genes and Caloric Restriction

Ames dwarf (Prop1 (df/df)) mice are remarkably long-lived and exhibit many characteristics of delayed aging and extended healthspan. Caloric restriction (CR) has similar effects on healthspan and lifespan, and causes an extension of longevity in Ames dwarf mice. Our study objective was to determine...

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Detalles Bibliográficos
Main Authors: Arum, Oge, Rasche, Zachary Andrew, Rickman, Dustin John, Bartke, Andrzej
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3796515/
https://ncbi.nlm.nih.gov/pubmed/24155868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072255
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