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Crystallization of the coiled-coil domain of Atg16 essential for autophagy
Atg16 is a scaffold protein that interacts with Atg12–Atg5 protein conjugates via its N-terminal domain and self-assembles via its coiled-coil domain, thus forming a multimeric Atg12–Atg5–Atg16 complex that is essential for autophagy. The coiled-coil domain of Atg16 was expressed, purified and cryst...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
International Union of Crystallography
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2581691/ https://ncbi.nlm.nih.gov/pubmed/18997338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108031898 |
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