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The IsdC Protein from Staphylococcus aureus Uses a Flexible Binding Pocket to Capture Heme

Staphylococcus aureus scavenges heme-iron from host hemoproteins using iron-regulated surface determinant (Isd) proteins. IsdC is the central conduit through which heme is passed across the cell wall and binds this molecule using a NEAr Transporter (NEAT) domain. NMR spectroscopy was used to determi...

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Bibliografische gegevens
Hoofdauteurs: Villareal, Valerie A., Pilpa, Rosemarie M., Robson, Scott A., Fadeev, Evgeny A., Clubb, Robert T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581589/
https://ncbi.nlm.nih.gov/pubmed/18715872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801126200
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