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The IsdC Protein from Staphylococcus aureus Uses a Flexible Binding Pocket to Capture Heme
Staphylococcus aureus scavenges heme-iron from host hemoproteins using iron-regulated surface determinant (Isd) proteins. IsdC is the central conduit through which heme is passed across the cell wall and binds this molecule using a NEAr Transporter (NEAT) domain. NMR spectroscopy was used to determi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2581589/ https://ncbi.nlm.nih.gov/pubmed/18715872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801126200 |
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