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Ferritin Contains Less Iron ((59)Fe) in Cells When the Protein Pores Are Unfolded by Mutation

Ferric minerals in ferritins are protected from cytoplasmic reductants and Fe(2+) release by the protein nanocage until iron need is signaled. Deletion of ferritin genes is lethal; two critical ferritin functions are concentrating iron and oxidant protection (consuming cytoplasmic iron and oxygen in...

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Xehetasun bibliografikoak
Egile Nagusiak: Hasan, Mohammad R., Tosha, Takehiko, Theil, Elizabeth C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581568/
https://ncbi.nlm.nih.gov/pubmed/18805796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806025200
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