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Ferritin Contains Less Iron ((59)Fe) in Cells When the Protein Pores Are Unfolded by Mutation
Ferric minerals in ferritins are protected from cytoplasmic reductants and Fe(2+) release by the protein nanocage until iron need is signaled. Deletion of ferritin genes is lethal; two critical ferritin functions are concentrating iron and oxidant protection (consuming cytoplasmic iron and oxygen in...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2581568/ https://ncbi.nlm.nih.gov/pubmed/18805796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806025200 |
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