Role of a Pro-sequence in the Secretory Pathway of Prothyrotropin-releasing Hormone

The biogenesis of rat thyrotropin releasing hormone (TRH) involves the processing of its precursor (proTRH) into five biologically active TRH peptides and several non-TRH peptides where two of them had been attributed potential biological functions. This process implicates 1) proper folding of proTR...

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Detalhes bibliográficos
Main Authors: Romero, Amparo, Çakir, Isin, Vaslet, Charles A., Stuart, Ronald C., Lansari, Omar, Lucero, Hector A., Nillni, Eduardo A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Protein Synthesis, Post-Translational Modification, and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581549/
https://ncbi.nlm.nih.gov/pubmed/18779326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803413200
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