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Prothyrotropin-releasing Hormone Targets Its Processing Products to Different Vesicles of the Secretory Pathway

Prothyrotropin-releasing hormone (pro-TRH) is initially cleaved by the prohormone convertase-1/3 (PC1/3) in the trans-Golgi network generating N- and C-terminal intermediate forms that are then packed into secretory vesicles. However, it is not known whether these peptides are differentially sorted...

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Detalhes bibliográficos
Main Authors: Perello, Mario, Stuart, Ronald, Nillni, Eduardo A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2459294/
https://ncbi.nlm.nih.gov/pubmed/18474603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800732200
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