Aurora A Is Essential for Early Embryonic Development and Tumor Suppression

Aurora A is a serine/threonine kinase that functions in various stages of mitosis. Accumulating evidence has demonstrated that gene amplification and overexpression of Aurora A are linked to tumorigenesis, suggesting that Aurora A is an oncogene. In addition, Aurora A overexpression has been used as...

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Bibliografiske detaljer
Main Authors: Lu, Lin-Yu, Wood, Jamie L., Ye, Lin, Minter-Dykhouse, Katherine, Saunders, Thomas L., Yu, Xiaochun, Chen, Junjie
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Molecular Basis of Cell and Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581543/
https://ncbi.nlm.nih.gov/pubmed/18801727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805880200
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