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Polo-Like Kinase 1 Is Essential for Early Embryonic Development and Tumor Suppression

Polo-like kinases (Plks) are serine/threonine kinases that are highly conserved in organisms from yeasts to humans. Previous reports have shown that Plk1 is critical for all stages of mitosis and may play a role in DNA replication during S phase. While much work has focused on Plk1, little is known...

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Detalhes bibliográficos
Main Authors: Lu, Lin-Yu, Wood, Jamie L., Minter-Dykhouse, Katherine, Ye, Lin, Saunders, Thomas L., Yu, Xiaochun, Chen, Junjie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573299/
https://ncbi.nlm.nih.gov/pubmed/18794363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00392-08
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