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Role of Rac in controlling the actin cytoskeleton and chemotaxis in motile cells

We have used the chemotactic ability of Dictyostelium cells to examine the roles of Rho family members, known regulators of the assembly of F-actin, in cell movement. Wild-type cells polarize with a leading edge enriched in F-actin toward a chemoattractant. Overexpression of constitutively active Di...

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Bibliografski detalji
Glavni autori: Chung, Chang Y., Lee, Susan, Briscoe, Celia, Ellsworth, Charlene, Firtel, Richard A.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2000
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC25810/
https://ncbi.nlm.nih.gov/pubmed/10805781
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