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Dictyostelium Dock180-related RacGEFs Regulate the Actin Cytoskeleton during Cell Motility

Cell motility of amoeboid cells is mediated by localized F-actin polymerization that drives the extension of membrane protrusions to promote forward movements. We show that deletion of either of two members of the Dictyostelium Dock180 family of RacGEFs, DockA and DockD, causes decreased speed of ch...

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Главные авторы: Para, Alessia, Krischke, Miriam, Merlot, Sylvain, Shen, Zhouxin, Oberholzer, Michael, Lee, Susan, Briggs, Steven, Firtel, Richard A.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Cell Biology 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626555/
https://ncbi.nlm.nih.gov/pubmed/19037099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-09-0899
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