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In vivo and in vitro analysis of chloroquine resistance in Plasmodium falciparum isolates from Senegal

To determine the predictive value of chloroquine (CQ) resistance markers in Senegal, Plasmodium falciparum DNA polymorphisms in pfmdr1 and pfcrt were examined in relation to clinical outcome. Despite CQ treatment, 17% of patients had parasitemia after 28 days. Examination of molecular markers of CQ...

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主要な著者: Sarr, Ousmane, Myrick, Alissa, Daily, Johanna, Diop, Bernard M., Dieng, Therese, Ndir, Omar, Sow, Pape Salif, Mboup, Souleymane, Wirth, Dyann F.
フォーマット: Artigo
言語:Inglês
出版事項: 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579896/
https://ncbi.nlm.nih.gov/pubmed/15986248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00436-005-1406-7
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