Prevalence of Plasmodium falciparum pfcrt polymorphisms and in vitro chloroquine sensitivity in Senegal

Mutations in pfcrt K76T are associated with chloroquine resistance in Plasmodium falciparum. Previous studies of K76T mutations in Senegal reported the association of T76 with in vitro-resistant isolates, but this mutation was also prevalent in chloroquine-sensitive isolates. This suggests involveme...

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Autori principali: Daily, J. P., Roberts, C., Thomas, S. M., Ndir, O., Dieng, T., Mboup, S., Wirth, D. F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2003
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582402/
https://ncbi.nlm.nih.gov/pubmed/12793643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S0031182003002981
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