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In vivo and in vitro analysis of chloroquine resistance in Plasmodium falciparum isolates from Senegal
To determine the predictive value of chloroquine (CQ) resistance markers in Senegal, Plasmodium falciparum DNA polymorphisms in pfmdr1 and pfcrt were examined in relation to clinical outcome. Despite CQ treatment, 17% of patients had parasitemia after 28 days. Examination of molecular markers of CQ...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2579896/ https://ncbi.nlm.nih.gov/pubmed/15986248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00436-005-1406-7 |
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