Novel interactions between the 5-HT transporter, 5-HT(1B) receptors and Rho kinase in vivo and in pulmonary fibroblasts

BACKGROUND AND PURPOSE: While the 5-HT and Rho-kinase (ROCK) pathways have been implicated in the development of pulmonary arterial hypertension (PAH), the nature of any interactions between them remain unclear. This study investigated a role for ROCK in 5-HT-regulated proliferative responses in lun...

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Autori principali: Mair, K M, MacLean, M R, Morecroft, I, Dempsie, Y, Palmer, T M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2008
Soggetti:
Research Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579673/
https://ncbi.nlm.nih.gov/pubmed/18695640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.310
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