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5-HT moduline: an endogenous inhibitor of 5-HT(1B/1D)-mediated contraction in pulmonary arteries

1. 5-HT moduline (5-HTm) is tetrapeptide (Leu-Ser-Ala-Leu) previously shown to act as a specific endogenous antagonist to central 5-HT(1B/1D) receptors. Its effects were investigated in rat and rabbit pulmonary arteries (PAs). 2. In rabbit PAs, contractile responses to the 5-HT(1B/1D) receptor agoni...

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Detalhes bibliográficos
Main Authors: Murdoch, R, Morecroft, I, MacLean, M R
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573734/
https://ncbi.nlm.nih.gov/pubmed/12642380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705123
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