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Increased contractile response to 5-hydroxytryptamine(1)-receptor stimulation in pulmonary arteries from chronic hypoxic rats: role of pharmacological synergy

1. 5-Hydroxytryptamine (5-HT)(1)-receptor-induced contraction is enhanced, or uncovered, by elevated vascular tone in many arteries including pulmonary arteries. In hypoxia-induced pulmonary hypertension, the endogenous tone of pulmonary arteries is elevated and this may contribute to increased 5-HT...

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Detalhes bibliográficos
Main Authors: MacLean, Margaret R, Morecroft, Ian
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572973/
https://ncbi.nlm.nih.gov/pubmed/11588116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704273
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