Tumor BRCA1, RRM1 and RRM2 mRNA Expression Levels and Clinical Response to First-Line Gemcitabine plus Docetaxel in Non-Small-Cell Lung Cancer Patients

BACKGROUND: Overexpression of RRM1 and RRM2 has been associated with gemcitabine resistance. BRCA1 overexpression increases sensitivity to paclitaxel and docetaxel. We have retrospectively examined the effect of RRM1, RRM2 and BRCA1 expression on outcome to gemcitabine plus docetaxel in advanced non...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Boukovinas, Ioannis, Papadaki, Chara, Mendez, Pedro, Taron, Miquel, Mavroudis, Dimitris, Koutsopoulos, Anastasios, Sanchez-Ronco, Maria, Sanchez, Jose Javier, Trypaki, Maria, Staphopoulos, Eustathios, Georgoulias, Vassilis, Rosell, Rafael, Souglakos, John
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2008
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579656/
https://ncbi.nlm.nih.gov/pubmed/19002265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003695
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi