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β-Arrestin 2 is required for lysophosphatidic acid-induced NF-κB activation
Lysophosphatidic acid (LPA) is a bioactive phospholipid and binds to its receptors, a family of G protein-coupled receptors (GPCR), which initiates multiple signaling cascades and leads to activation of several transcription factors, including NF-κB. Although LPA-induced signaling pathways have been...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2579382/ https://ncbi.nlm.nih.gov/pubmed/18952848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802701105 |
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