Staged assembly of histone gene expression machinery at subnuclear foci in the abbreviated cell cycle of human embryonic stem cells

Human embryonic stem (hES) cells have an abbreviated G(1) phase of the cell cycle. How cells expedite G(1) events that are required for the initiation of S phase has not been resolved. One key regulatory pathway that controls G(1)/S-phase transition is the cyclin E/CDK2-dependent activation of the c...

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Bibliographic Details
Main Authors: Ghule, Prachi N., Dominski, Zbigniew, Yang, Xiao-cui, Marzluff, William F., Becker, Klaus A., Harper, J. Wade, Lian, Jane B., Stein, Janet L., van Wijnen, Andre J., Stein, Gary S.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2008
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579361/
https://ncbi.nlm.nih.gov/pubmed/18957539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809273105
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