Staged assembly of histone gene expression machinery at subnuclear foci in the abbreviated cell cycle of human embryonic stem cells

Human embryonic stem (hES) cells have an abbreviated G(1) phase of the cell cycle. How cells expedite G(1) events that are required for the initiation of S phase has not been resolved. One key regulatory pathway that controls G(1)/S-phase transition is the cyclin E/CDK2-dependent activation of the c...

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Autors principals: Ghule, Prachi N., Dominski, Zbigniew, Yang, Xiao-cui, Marzluff, William F., Becker, Klaus A., Harper, J. Wade, Lian, Jane B., Stein, Janet L., van Wijnen, Andre J., Stein, Gary S.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579361/
https://ncbi.nlm.nih.gov/pubmed/18957539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809273105
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