Lack of association of two common polymorphisms on 9p21 with risk of coronary heart disease and myocardial infarction; results from a prospective cohort study

BACKGROUND: Recent genome wide association (GWA) studies identified two Single Nucleotide Polymorphisms (SNP) (rs10757278 and rs10757274) in the region of the CDK2NA and CDK2NB genes to be consistently associated with the risks of coronary heart disease (CHD) and myocardial infarction (MI). We exami...

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Hlavní autoři: Dehghan, Abbas, van Hoek, Mandy, Sijbrands, Eric JG, Oostra, Ben A, Hofman, Albert, van Duijn, Cornelia M, Witteman, Jacqueline CM
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579294/
https://ncbi.nlm.nih.gov/pubmed/18925945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7015-6-30
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