SIRT1 Genetic Variation Is Related to BMI and Risk of Obesity

OBJECTIVE: SIRT1 has pleiotropic metabolic functions. We investigated whether SIRT1 genetic variation is associated with obesity. RESEARCH DESIGN AND METHODS: In 6,251 elderly subjects from the prospective, population-based Rotterdam Study, three single nucleotide polymorphisms (SNPs) in the SIRT1 g...

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Detalhes bibliográficos
Main Authors: Zillikens, M.Carola, van Meurs, Joyce B.J., Rivadeneira, Fernando, Amin, Najaf, Hofman, Albert, Oostra, Ben A., Sijbrands, Eric J.G., Witteman, Jacqueline C.M., Pols, Huibert A.P., van Duijn, Cornelia M., Uitterlinden, André G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780870/
https://ncbi.nlm.nih.gov/pubmed/19741164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0536
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