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Variance heterogeneity analysis for detection of potentially interacting genetic loci: method and its limitations

BACKGROUND: Presence of interaction between a genotype and certain factor in determination of a trait's value, it is expected that the trait's variance is increased in the group of subjects having this genotype. Thus, test of heterogeneity of variances can be used as a test to screen for p...

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Autori principali: Struchalin, Maksim V, Dehghan, Abbas, Witteman, Jacqueline CM, van Duijn, Cornelia, Aulchenko, Yurii S
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2973850/
https://ncbi.nlm.nih.gov/pubmed/20942902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-11-92
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