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Overexpressed mitochondrial leucyl-tRNA synthetase suppresses the A3243G mutation in the mitochondrial tRNA(Leu(UUR)) gene

The A3243G mutation in the human mitochondrial tRNA(Leu(UUR)) gene causes a number of human diseases. This mutation reduces the level and fraction of aminoacylated tRNA(Leu(UUR)) and eliminates nucleotide modification at the wobble position of the anticodon. These deficiencies are associated with mi...

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Detaylı Bibliyografya
Asıl Yazarlar: Park, Hyejeong, Davidson, Edgar, King, Michael P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2578859/
https://ncbi.nlm.nih.gov/pubmed/18796578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1208808
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