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Electrostatic contributions drive the interaction between Staphylococcus aureus protein Efb-C and its complement target C3d
The C3–inhibitory domain of Staphylococcus aureus extracellular fibrinogen-binding protein (Efb-C) defines a novel three-helix bundle motif that regulates complement activation. Previous crystallographic studies of Efb-C bound to its cognate subdomain of human C3 (C3d) identified Arg-131 and Asn-138...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2578803/ https://ncbi.nlm.nih.gov/pubmed/18687868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.036624.108 |
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