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Multi-scale Characterization of the Energy Landscape of Proteins with Application to the C3d/Efb-C Complex

We present a novel multi-level methodology to explore and characterize the low energy landscape and the thermodynamics of proteins. Traditional conformational search methods typically explore only a small portion of the conformational space of proteins and are hard to apply to large proteins due to...

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Detalhes bibliográficos
Main Authors: Haspel, Nurit, Geisbrecht, Brian V., Lambris, John, Kavraki, Lydia
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827694/
https://ncbi.nlm.nih.gov/pubmed/19899169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22624
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