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Solution Insights into the Structure of the Efb/C3 Complement Inhibitory Complex as Revealed by Lysine Acetylation and Mass Spectrometry

The extracellular fibrinogen-binding protein (Efb), an immunosuppressive and anti-inflammatory protein secreted by Staphylococcus aureus, has been identified as a potent inhibitor of complement-mediated innate immunity. Efb functions by binding to and disrupting the function of complement component...

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Detalhes bibliográficos
Main Authors: Chen, Hui, Schuster, Michael C., Sfyroera, Georgia, Geisbrecht, Brian V., Lambris, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775528/
https://ncbi.nlm.nih.gov/pubmed/18293486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jasms.2007.10.009
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