Uracil-DNA glycosylase–DNA substrate and product structures: Conformational strain promotes catalytic efficiency by coupled stereoelectronic effects

Enzymatic transformations of macromolecular substrates such as DNA repair enzyme/DNA transformations are commonly interpreted primarily by active-site functional-group chemistry that ignores their extensive interfaces. Yet human uracil–DNA glycosylase (UDG), an archetypical enzyme that initiates DNA...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Parikh, Sudip S., Walcher, Gunter, Jones, Garry D., Slupphaug, Geir, Krokan, Hans E., Blackburn, G. Michael, Tainer, John A.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2000
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC25785/
https://ncbi.nlm.nih.gov/pubmed/10805771
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars