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A defect of sphingolipid metabolism modifies the properties of normal appearing white matter in multiple sclerosis

Maintaining the appropriate complement and content of lipids in cellular membranes is critical for normal neural function. Accumulating evidence suggests that even subtle perturbations in the lipid content of neurons and myelin can disrupt their function and may contribute to myelin and axonal degra...

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Bibliografiske detaljer
Main Authors: Wheeler, David, Bandaru, Veera Venkata Ratnam, Calabresi, Peter A., Nath, Avindra, Haughey, Norman J.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577809/
https://ncbi.nlm.nih.gov/pubmed/18772223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awn190
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