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A defect of sphingolipid metabolism modifies the properties of normal appearing white matter in multiple sclerosis

Maintaining the appropriate complement and content of lipids in cellular membranes is critical for normal neural function. Accumulating evidence suggests that even subtle perturbations in the lipid content of neurons and myelin can disrupt their function and may contribute to myelin and axonal degra...

詳細記述

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書誌詳細
主要な著者: Wheeler, David, Bandaru, Veera Venkata Ratnam, Calabresi, Peter A., Nath, Avindra, Haughey, Norman J.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577809/
https://ncbi.nlm.nih.gov/pubmed/18772223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awn190
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