Role of ompR-dependent genes in Salmonella typhimurium virulence: mutants deficient in both ompC and ompF are attenuated in vivo.

A Salmonella typhimurium strain harboring stable mutations in both ompC and ompF was constructed from the mouse-virulent strain S. typhimurium SL1344. When administered orally to BALB/c mice the strain was attenuated, with the 50% lethal dose (LD50) reduced by approximately 1,000-fold. However, the...

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-д хэвлэсэн:	Infect Immun
Үндсэн зохиолчид:	Chatfield, S N, Dorman, C J, Hayward, C, Dougan, G
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	American Society for Microbiology (ASM) 1991
Нөхцлүүд:	Research Article
Онлайн хандалт:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257763/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1846127/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.1.449-452.1991
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