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Role of ompR-dependent genes in Salmonella typhimurium virulence: mutants deficient in both ompC and ompF are attenuated in vivo.

A Salmonella typhimurium strain harboring stable mutations in both ompC and ompF was constructed from the mouse-virulent strain S. typhimurium SL1344. When administered orally to BALB/c mice the strain was attenuated, with the 50% lethal dose (LD50) reduced by approximately 1,000-fold. However, the...

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Библиографические подробности
Главные авторы: Chatfield, S N, Dorman, C J, Hayward, C, Dougan, G
Формат: Artigo
Язык:Inglês
Опубликовано: 1991
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC257763/
https://ncbi.nlm.nih.gov/pubmed/1846127
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