Role of ompR-dependent genes in Salmonella typhimurium virulence: mutants deficient in both ompC and ompF are attenuated in vivo.

A Salmonella typhimurium strain harboring stable mutations in both ompC and ompF was constructed from the mouse-virulent strain S. typhimurium SL1344. When administered orally to BALB/c mice the strain was attenuated, with the 50% lethal dose (LD50) reduced by approximately 1,000-fold. However, the...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Infect Immun
Hauptverfasser:	Chatfield, S N, Dorman, C J, Hayward, C, Dougan, G
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257763/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1846127/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.1.449-452.1991
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!