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Allene–alkyne cross-coupling for stereoselective synthesis of substituted 1,4-dienes and cross-conjugated trienes

Titanium-mediated cross-coupling of allenic alcohols with alkynes has been investigated. Divergent reaction pathways were discovered that provide either stereodefined 1,4-dienes or substituted cross-conjugated trienes. In short, allene substitution plays a critical role in the determination of react...

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Détails bibliographiques
Auteurs principaux: Shimp, Heidi L., Hare, Alissa, McLaughlin, Martin, Micalizio, Glenn C.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577592/
https://ncbi.nlm.nih.gov/pubmed/18985173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2008.02.015
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