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Protein Arginine Methyltransferase 5 Suppresses the Transcription of the RB Family of Tumor Suppressors in Leukemia and Lymphoma Cells

The proper epigenetic modification of chromatin by protein arginine methyltransferases (PRMTs) is crucial for normal cell growth and health. The human SWI/SNF-associated PRMT5 is involved in the transcriptional repression of target genes by directly methylating H3R8 and H4R3. To further understand t...

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Bibliografski detalji
Glavni autori: Wang, Li, Pal, Sharmistha, Sif, Saïd
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577430/
https://ncbi.nlm.nih.gov/pubmed/18694959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00923-08
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