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The Catalytic Subunit of DNA-Dependent Protein Kinase Regulates Proliferation, Telomere Length, and Genomic Stability in Human Somatic Cells

The DNA-dependent protein kinase (DNA-PK) complex is a serine/threonine protein kinase comprised of a 469-kDa catalytic subunit (DNA-PK(cs)) and the DNA binding regulatory heterodimeric (Ku70/Ku86) complex Ku. DNA-PK functions in the nonhomologous end-joining pathway for the repair of DNA double-str...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Ruis, Brian L., Fattah, Kazi R., Hendrickson, Eric A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577426/
https://ncbi.nlm.nih.gov/pubmed/18710952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00355-08
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