Detection of a Molecular Biomarker for Zygomycetes by Quantitative PCR Assays of Plasma, Bronchoalveolar Lavage, and Lung Tissue in a Rabbit Model of Experimental Pulmonary Zygomycosis

We developed two real-time quantitative PCR (qPCR) assays, targeting the 28S rRNA gene, for the diagnosis of zygomycosis caused by the most common, clinically significant Zygomycetes. The amplicons of the first qPCR assay (qPCR-1) from Rhizopus, Mucor, and Rhizomucor species were distinguished throu...

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Detalhes bibliográficos
Main Authors: Kasai, Miki, Harrington, Susan M., Francesconi, Andrea, Petraitis, Vidmantas, Petraitiene, Ruta, Beveridge, Mara G., Knudsen, Tena, Milanovich, Jeffery, Cotton, Margaret P., Hughes, Johanna, Schaufele, Robert L., Sein, Tin, Bacher, John, Murray, Patrick R., Kontoyiannis, Dimitrios P., Walsh, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Mycology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576616/
https://ncbi.nlm.nih.gov/pubmed/18845827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00917-08
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