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Structural Insights into the Role of Mutations in Amyloidogenesis

Mechanisms of amyloidogenesis are not well understood, including potential structural contributions of mutations in the process. Our previous research indicated that the dimer interface of amyloidogenic immunoglobulin light chain protein AL-09 is twisted 90° relative to the protein from its germline...

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Autors principals: Baden, Elizabeth M., Randles, Edward G., Aboagye, Awo K., Thompson, James R., Ramirez-Alvarado, Marina
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576559/
https://ncbi.nlm.nih.gov/pubmed/18768467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804822200
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