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Partially Irreversible Inactivation of Mitochondrial Aldehyde Dehydrogenase by Nitroglycerin

Mitochondrial aldehyde dehydrogenase (ALDH2) may be involved in the biotransformation of glyceryl trinitrate (GTN), and the inactivation of ALDH2 by GTN may contribute to the phenomenon of nitrate tolerance. We studied the GTN-induced inactivation of ALDH2 by UV/visible absorption spectroscopy. Dehy...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Beretta, Matteo, Sottler, Astrid, Schmidt, Kurt, Mayer, Bernd, Gorren, Antonius C. F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576553/
https://ncbi.nlm.nih.gov/pubmed/18786921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804001200
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