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Cartilage Aggrecan Can Undergo Self-Adhesion

Here it is reported that aggrecan, the highly negatively charged macromolecule in the cartilage extracellular matrix, undergoes Ca(2+)-mediated self-adhesion after static compression even in the presence of strong electrostatic repulsion in physiological-like solution conditions. Aggrecan was chemic...

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Bibliografiske detaljer
Main Authors: Han, Lin, Dean, Delphine, Daher, Laura A., Grodzinsky, Alan J., Ortiz, Christine
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576402/
https://ncbi.nlm.nih.gov/pubmed/18676640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.128389
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