Single-Molecule Force Spectroscopy of Cartilage Aggrecan Self-Adhesion

We investigated self-adhesion between highly negatively charged aggrecan macromolecules extracted from bovine cartilage extracellular matrix by performing atomic force microscopy (AFM) imaging and single-molecule force spectroscopy (SMFS) in saline solutions. By controlling the density of aggrecan m...

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Bibliographic Details
Main Authors: Harder, Alexander, Walhorn, Volker, Dierks, Thomas, Fernàndez-Busquets, Xavier, Anselmetti, Dario
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2010
Subjects:
Spectroscopy, Imaging, and Other Techniques
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980716/
https://ncbi.nlm.nih.gov/pubmed/21081100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.09.002
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