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Downregulation of KSR1 in pancreatic cancer xenografts by antisense oligonucleotide correlates with tumor drug uptake

While antisense oligonucleotide (AS-ODN) technology holds promise for the treatment of cancer, to date there have been no clinical successes. Unfortunately, current assays are not sufficiently sensitive to measure tissue ODN levels. Hence it has not been possible to ascertain whether treatment failu...

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Autori principali: Zhang, Jianjun, Zafrullah, Mohammad, Yang, Xia, Yin, Xianglei, Zhang, Zhigang, Fuks, Zvi, Kolesnick, Richard
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576298/
https://ncbi.nlm.nih.gov/pubmed/18719367
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